Mutation and Transmission Profiles of Second-Line Drug Resistance in Clinical Isolates of Drug-Resistant Mycobacterium tuberculosis From Hebei Province, China

Mutation and Transmission Profiles of Second-Line Drug Resistance in Clinical Isolates of Drug-Resistant Mycobacterium tuberculosis From Hebei Province, China

The emergence of drug-resistant tuberculosis (TB) is involved in ineffective treatment of TB, especially multidrug resistant/extensively resistant TB (MDR/XDR-TB), leading to acquired resistance and transmission of drug-resistant strains. Second-line drugs (SLD), including both fluoroquinolones and...

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Bibliographic Details
Main Authors: Qianlin Li, Huixia Gao, Zhi Zhang, Yueyang Tian, Tengfei Liu, Yuling Wang, Jianhua Lu, Yuzhen Liu, Erhei Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Microbiology
Subjects:
second-line anti-tuberculosis drugs
Mycobacterium tuberculosis
associated-resistance mutation
acquired resistance
genotype
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01838/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.01838/full

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