Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host

Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host

Abstract Background Recent metagenomic analyses have revealed dysbiosis of the gut microbiota of ulcerative colitis (UC) patients. However, the impacts of this dysbiosis are not fully understood, particularly at the strain level. Results We perform whole-genome shotgun sequencing of fecal DNA extrac...

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Bibliographic Details
Main Authors: Jun Seishima, Noriho Iida, Kazuya Kitamura, Masahiro Yutani, Ziyu Wang, Akihiro Seki, Taro Yamashita, Yoshio Sakai, Masao Honda, Tatsuya Yamashita, Takashi Kagaya, Yukihiro Shirota, Yukako Fujinaga, Eishiro Mizukoshi, Shuichi Kaneko
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Genome Biology
Subjects:
Inflammatory bowel disease
Crohn’s disease
Microbiota
Metagenome
Online Access:http://link.springer.com/article/10.1186/s13059-019-1879-9

Internet

http://link.springer.com/article/10.1186/s13059-019-1879-9

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