Analysis of HETEs in human whole blood by chiral UHPLC-ECAPCI/HRMS

Analysis of HETEs in human whole blood by chiral UHPLC-ECAPCI/HRMS

The biosynthesis of eicosanoids occurs enzymatically via lipoxygenases, cyclooxygenases, and cytochrome P450, or through nonenzymatic free radical reactions. The enzymatic routes are highly enantiospecific. Chiral separation and high-sensitivity detection methods are required to differentiate and qu...

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Bibliographic Details
Main Authors: Liudmila L. Mazaleuskaya, Ashkan Salamatipour, Dimitra Sarantopoulou, Liwei Weng, Garret A. FitzGerald, Ian A. Blair, Clementina Mesaros
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Journal of Lipid Research
Subjects:
chiral hydroxyeicosatetraenoic acids
human blood
plasma lipidomics
serum lipidomics
coagulation
hydroxyeicosatetraenoic acids
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520331436

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http://www.sciencedirect.com/science/article/pii/S0022227520331436

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