Effects of N-acetylcysteine on amphetamine-induced sensitization in mice

Objective: N-acetylcysteine (NAC) is beneficial in psychiatric conditions, including schizophrenia. Patients with schizophrenia exhibit mesolimbic dopamine hyperfunction consequent to an endogenous sensitization process. This sensitization can be modeled in rodents by repeated exposure to psychostim...

Full description

Bibliographic Details
Main Authors: Ana P. Herrmann, Roberta Andrejew, Radharani Benvenutti, Clarissa S. Gama, Elaine Elisabetsky
Format: Article
Language:English
Published: Associação Brasileira de Psiquiatria (ABP) 2017-12-01
Series:Brazilian Journal of Psychiatry
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462017005020103&lng=en&tlng=en