Neuroanatomical Quantitative Proteomics Reveals Common Pathogenic Biological Routes between Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

Neuroanatomical Quantitative Proteomics Reveals Common Pathogenic Biological Routes between Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

(1) Background: Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative disorders with an overlap in clinical presentation and neuropathology. Common and differential mechanisms leading to protein expression changes and neurodegeneration in ALS and FTD were studie...

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Bibliographic Details
Main Authors: Marina Oaia Iridoy, Irene Zubiri, María Victoria Zelaya, Leyre Martinez, Karina Ausín, Mercedes Lachen-Montes, Enrique Santamaría, Joaquín Fernandez-Irigoyen, Ivonne Jericó
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
amyotrophic lateral sclerosis (ALS)
frontotemporal dementia (FTD)
motor neuron
proteomics
Online Access:https://www.mdpi.com/1422-0067/20/1/4

Internet

https://www.mdpi.com/1422-0067/20/1/4

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