IP-10 Promotes Latent HIV Infection in Resting Memory CD4+ T Cells via LIMK-Cofilin Pathway

IP-10 Promotes Latent HIV Infection in Resting Memory CD4+ T Cells via LIMK-Cofilin Pathway

A major barrier to HIV eradication is the persistence of viral reservoirs. Resting CD4+ T cells are thought to be one of the major viral reservoirs, However, the underlying mechanism regulating HIV infection and the establishment of viral reservoir in T cells remain poorly understood. We have invest...

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Bibliographic Details
Main Authors: Zhuo Wang, Xiaowan Yin, Meichen Ma, Hongchi Ge, Bin Lang, Hong Sun, Sijia He, Yajing Fu, Yu Sun, Xiaowen Yu, Zining Zhang, Hualu Cui, Xiaoxu Han, Junjie Xu, Haibo Ding, Zhenxing Chu, Hong Shang, Yuntao Wu, Yongjun Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
CXCL10
resting memory CD4+ T cells
latent infection
HIV reservoir
cofilin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.656663/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.656663/full

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