Effect of Piperine on Caffeine Salivary Concentration in Healthy Volunteers

BACKGROUND AND OBJECTIVE: Piperine (the alkaloid of piper nigrum) can change the activities of microsomal enzymes. Caffeine probe were applied to determination of CYP1A2 enzyme activity. CYP1A2 enzyme is important enzymes in drugs metabolism that induces over 13% of liver cytochromes. This study was...

Full description

Bibliographic Details
Main Authors: A Gholampour, M Hashemi, MM Rezaee, MR Shiran, AA Moghadamnia
Format: Article
Language:English
Published: Babol University of Medical Sciences 2013-07-01
Series:Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
Subjects:
Online Access:http://jbums.org/article-1-4464-en.html