Phosphorylcholine allows for evasion of bactericidal antibody by Haemophilus influenzae.

The human pathogen Haemophilus influenzae has the ability to quickly adapt to different host environments through phase variation of multiple structures on its lipooligosaccharide (LPS), including phosphorylcholine (ChoP). During colonization with H. influenzae, there is a selection for ChoP+ phase...

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Bibliographic Details
Main Authors: Sarah E Clark, Julian Snow, Jianjun Li, Tracey A Zola, Jeffrey N Weiser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3291618?pdf=render