A Tiered Genetic Screening Strategy for the Molecular Diagnosis of Intellectual Disability in Chinese Patients

A Tiered Genetic Screening Strategy for the Molecular Diagnosis of Intellectual Disability in Chinese Patients

Objective: Intellectual disability (ID) is one of the most common developmental disabilities. To identify the genetic etiology of IDs in Chongqing, we conducted a multistage study in Chinese Han patients.Methods: We collected the clinical and etiological data of 1665 ID patients, including 1,604 fro...

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Bibliographic Details
Main Authors: Limeng Dai, Danyan Zhang, Zhifeng Wu, Xingying Guan, Mingfu Ma, Lianbing Li, Yuping Zhang, Yun Bai, Hong Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Genetics
Subjects:
whole exome sequencing (WES)
chromosomal microarray (CMA)
copy number variation (CNV)
developmental delays (DD)
intellectual disability (ID)
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.669217/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.669217/full

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