Aspirin alone and combined with a statin suppresses eicosanoid formation in human colon tissue[S]

Aspirin alone and combined with a statin suppresses eicosanoid formation in human colon tissue[S]

Eicosanoids, including prostaglandins (PGs) and thromboxanes, are broadly bioactive lipid mediators and increase colon tumorigenesis possibly through chronic inflammatory mechanisms. Epidemiological and experimental data suggest that acetylsalicylic acid (ASA) helps prevent colorectal cancer (CRC),...

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Bibliographic Details
Main Authors: Heike Gottschall, Christoph Schmöcker, Dirk Hartmann, Nadine Rohwer, Katharina Rund, Laura Kutzner, Fabian Nolte, Annika I. Ostermann, Nils Helge Schebb, Karsten H. Weylandt
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Lipid Research
Subjects:
colorectal cancer
lipidomics
cyclooxygenase
arachidonic acid
acetylsalicylic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520331217

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520331217

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