Modeling Congenital Disorders of N-Linked Glycoprotein Glycosylation in Drosophila melanogaster

Modeling Congenital Disorders of N-Linked Glycoprotein Glycosylation in Drosophila melanogaster

Protein glycosylation, the enzymatic addition of N-linked or O-linked glycans to proteins, serves crucial functions in animal cells and requires the action of glycosyltransferases, glycosidases and nucleotide-sugar transporters, localized in the endoplasmic reticulum and Golgi apparatus. Congenital...

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Bibliographic Details
Main Authors: Anna Frappaolo, Stefano Sechi, Tadahiro Kumagai, Angela Karimpour-Ghahnavieh, Michael Tiemeyer, Maria Grazia Giansanti
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Genetics
Subjects:
Drosophila
glycosylation
congenital disorders
Golgi
model organism
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00436/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00436/full

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