UHPLC–Q/Orbitrap/MS/MS fingerprinting and antitumoral effects of Prosopis strombulifera (LAM.) BENTH. queous extract on allograft colorectal and melanoma cancer models

UHPLC–Q/Orbitrap/MS/MS fingerprinting and antitumoral effects of Prosopis strombulifera (LAM.) BENTH. queous extract on allograft colorectal and melanoma cancer models

The aqueous extract of the Argentinean native plant, Prosopis strombulifera (PsAE), presents cytotoxicity against human cancer cell lines by inducing cytostasis, necrosis and apoptosis; with diminution of clonogenic survival; without genotoxic effects nor oral animal toxicity. Until now, the chemica...

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Bibliographic Details
Main Authors: Fabio Andrés Persia, Mariana Elizabeth Troncoso, Estefanía Rinaldini, Mario Simirgiotis, Alejandro Tapia, Jorge Bórquez, Juan Pablo Mackern-Oberti, María Belén Hapon, Carlos Gamarra-Luques
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Heliyon
Subjects:
Cancer research
Cell biology
Toxicology
Cell culture
Cell death
Cytotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020301985

Internet

http://www.sciencedirect.com/science/article/pii/S2405844020301985

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