Targeting Ubiquitin-Specific Protease 7 (USP7) in Cancer: A New Insight to Overcome Drug Resistance

Targeting Ubiquitin-Specific Protease 7 (USP7) in Cancer: A New Insight to Overcome Drug Resistance

Chemoresistance is one of the leading causes for the failure of tumor treatment. Hence, it is necessary to study further and understand the potential mechanisms of tumor resistance to design and develop novel anti-tumor drugs. Post-translational modifications are critical for proteins’ function unde...

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Bibliographic Details
Main Authors: Jiabin Lu, He Zhao, Caini Yu, Yuanyuan Kang, Xiaochun Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
tumor therapy resistance
ubiquitination modification
ubiquitin-proteasome system
ubiquitin-specific protease 7
deubiquitinases
USP7 inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.648491/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.648491/full

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