The DNA copy number of human endogenous retrovirus-W (MSRV-type) is increased in multiple sclerosis patients and is influenced by gender and disease severity.

The DNA copy number of human endogenous retrovirus-W (MSRV-type) is increased in multiple sclerosis patients and is influenced by gender and disease severity.

BACKGROUND: Multiple sclerosis is an autoimmune disease more prevalent in women than in men. Multiple Sclerosis Associated Retrovirus element (MSRV) is a member of type-W endogenous retrovirus family (HERV-W), known to be associated to MS. Most HERVs are unable to replicate but MSRV expression assoc...

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Bibliographic Details
Main Authors: Marta Garcia-Montojo, María Dominguez-Mozo, Ana Arias-Leal, Ángel Garcia-Martinez, Virginia De las Heras, Ignacio Casanova, Raphaël Faucard, Nadège Gehin, Alexandra Madeira, Rafael Arroyo, François Curtin, Roberto Alvarez-Lafuente, Hervé Perron
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3538585?pdf=render

Internet

http://europepmc.org/articles/PMC3538585?pdf=render

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