Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection

The antibody response during infection with dengue virus is a key component involved in the pathogenesis during secondary infection. Here the authors show antibodies targeting NS1 and the epitopes targeted can be associated with disease severity during human infection.

Bibliographic Details
Main Authors: Deshni Jayathilaka, Laksiri Gomes, Chandima Jeewandara, Geethal. S. Bandara Jayarathna, Dhanushka Herath, Pathum Asela Perera, Samitha Fernando, Ananda Wijewickrama, Clare S. Hardman, Graham S. Ogg, Gathsaurie Neelika Malavige
Format: Article
Language:English
Published: Nature Publishing Group 2018-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07667-z