A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.

A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.

No single animal model for severe acute respiratory syndrome (SARS) reproduces all aspects of the human disease. Young inbred mice support SARS-coronavirus (SARS-CoV) replication in the respiratory tract and are available in sufficient numbers for statistical evaluation. They are relatively inexpens...

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Bibliographic Details
Main Authors: Anjeanette Roberts, Damon Deming, Christopher D Paddock, Aaron Cheng, Boyd Yount, Leatrice Vogel, Brian D Herman, Tim Sheahan, Mark Heise, Gillian L Genrich, Sherif R Zaki, Ralph Baric, Kanta Subbarao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1769406?pdf=render

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http://europepmc.org/articles/PMC1769406?pdf=render

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