Phosphatidylinositol 3'-kinase, mTOR, and Glycogen synthase kinase-3β mediated regulation of p21 in human urothelial carcinoma cells

<p>Abstract</p> <p>Background</p> <p>The PTEN/Phosphatidylinositol 3'-kinase (PI3-kinase) growth factor signaling pathway plays a critical role in epithelial tumor development in a multitude of tissue types. Deletion of the <it>Pten </it>tumor suppresso...

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Bibliographic Details
Main Authors: DuMont Ashley L, Bingaman Caitlyn N, Yohn Nicole L, Yoo Lina I
Format: Article
Language:English
Published: BMC 2011-08-01
Series:BMC Urology
Online Access:http://www.biomedcentral.com/1471-2490/11/19