Mineralocorticoid Receptor in Myeloid Cells Mediates Angiotensin II-Induced Vascular Dysfunction in Female Mice

Mineralocorticoid Receptor in Myeloid Cells Mediates Angiotensin II-Induced Vascular Dysfunction in Female Mice

Enhanced mineralocorticoid receptor (MR) signaling is critical to the development of endothelial dysfunction and arterial stiffening. However, there is a lack of knowledge about the role of MR-induced adipose tissue inflammation in the genesis of vascular dysfunction in women. In this study, we hypo...

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Bibliographic Details
Main Authors: Camila Manrique-Acevedo, Jaume Padilla, Huma Naz, Makenzie L. Woodford, Thaysa Ghiarone, Annayya R. Aroor, Jack L. Hulse, Francisco J. Cabral-Amador, Vanesa Martinez-Diaz, Chetan P. Hans, Adam Whaley-Connell, Luis A. Martinez-Lemus, Guido Lastra
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
arterial stiffening
macrophage
endothelium
inflammation
adipose tissue
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.588358/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.588358/full

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