Norepinephrine modulates IL-1β-induced catabolic response of human chondrocytes

Abstract Background The influence of the sympathetic nervous system (SNS) on metabolism of bone and cartilage expressing β-adrenergic receptors (AR) was suggested. Here, we investigated whether the SNS functions as a modulator of cartilage metabolism induced by interleukin-1beta (IL-1β). Methods Hum...

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Bibliographic Details
Main Authors: Hyun Sook Hwang, Mi Hyun Lee, Dong Jin Go, Hyun Ah Kim
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12891-021-04598-7