Computational model of neuron-astrocyte interactions during focal seizure generation

Computational model of neuron-astrocyte interactions during focal seizure generation

Empirical research in the last decade revealed that astrocytes can respond to neurotransmitters with Ca2+ elevations and generate feedback signals to neurons which modulate synaptic transmission and neuronal excitability. This discovery changed our basic understanding of brain function and provided...

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Bibliographic Details
Main Authors: Davide eReato, Mario eCammarota, Lucas Cristobal Parra, Giorgio eCarmignoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Computational Neuroscience
Subjects:
Epilepsy
computational model
excitation/inhibition balance
neuron-astrocyte interaction
tripartite synapse
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncom.2012.00081/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncom.2012.00081/full

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