M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other monocyte/macrophage subtypes

M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other monocyte/macrophage subtypes

<p>Abstract</p> <p>Background</p> <p>In obesity, phenotypic switches occur in macrophage populations such that the predominantly M2-polarised anti-inflammatory state seen in lean individuals changes to a predominantly M1-polarised pro-inflammatory state in those who are...

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Bibliographic Details
Main Authors: Isa Suleiman A, Ruffino José S, Ahluwalia Maninder, Thomas Andrew W, Morris Keith, Webb Richard
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Lipids in Health and Disease
Subjects:
alternative M2 monocyte/macrophage polarisation
UPR
oxLDL
lipotoxicity
Online Access:http://www.lipidworld.com/content/10/1/229

Internet

http://www.lipidworld.com/content/10/1/229

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