DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke

DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke

Abstract Background Acute inflammation induced by reactive astrocytes after cerebral ischemia/reperfusion (I/R) injury is important for protecting the resultant lesion. Our previous study demonstrated that DJ-1 is abundantly expressed in reactive astrocytes after cerebral I/R injury. Here, we show t...

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Bibliographic Details
Main Authors: Li Peng, Yang Zhou, Ning Jiang, Tingting Wang, Jin Zhu, Yanlin Chen, Linyu Li, Jinyan Zhang, Shanshan Yu, Yong Zhao
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Neuroinflammation
Subjects:
Astrocyte
DJ-1
NLRX1-TRAF6
SHP-1
Inflammation
I/R injury
Online Access:http://link.springer.com/article/10.1186/s12974-020-01764-x

Internet

http://link.springer.com/article/10.1186/s12974-020-01764-x

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