Mapping the immune environment in clear cell renal carcinoma by single-cell genomics

Mapping the immune environment in clear cell renal carcinoma by single-cell genomics

Borcherding and Vishwakarma et al. characterize the tumor immune microenvironment in treatment-naïve clear cell renal carcinoma patients using single-cell RNA- and T-cell receptor sequencing. They find CD8 + T cells and macrophages are enriched in tumor tissue, and identify a proliferative CD8 + T-c...

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Bibliographic Details
Main Authors: Nicholas Borcherding, Ajaykumar Vishwakarma, Andrew P. Voigt, Andrew Bellizzi, Jacob Kaplan, Kenneth Nepple, Aliasger K. Salem, Russell W. Jenkins, Yousef Zakharia, Weizhou Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-020-01625-6

Internet

https://doi.org/10.1038/s42003-020-01625-6

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