MiR-301a Mediates the Effect of IL-6 on the AKT/GSK Pathway and Hepatic Glycogenesis by Regulating PTEN Expression

Background/Aims: IL-6 has been implicated in the pathogenesis of insulin resistance. MiR-301a plays an important role in various biological and pathological processes, including cellular development and differentiation, inflammation, apoptosis and cancer. However, whether miR-301a mediates IL-6-indu...

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Bibliographic Details
Main Authors: Lin Dou, Shuyue Wang, Xiaofang Sui, Xiangyu Meng, Tao Shen, Xiuqing Huang, Jun Guo, Weiwei Fang, Yong Man, Jianzhong Xi, Jian Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
AKT
Online Access:http://www.karger.com/Article/FullText/373962