CD4+ T Cells are Exhausted and Show Functional Defects in Chronic Lymphocytic Leukemia

<strong>Background:</strong> Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the western world. This health problem is caused due to the accumulation of mature B-lymphocytes in the peripheral blood and bone marrow. In the course of cancer, CD4+ T cells become “exh...

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Bibliographic Details
Main Authors: Esmaeil Allahmoradi, Saeid Taghiloo, Mohsen Tehrani, Hadi Hossein-Nattaj, Ghasem Janbabaei, Ramin Shekarriz, Hossein Asgarian-Omran
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2017-12-01
Series:Iranian Journal of Immunology
Subjects:
Online Access:http://iji.sums.ac.ir/article_39322_9029a913c61823fbc825e875436c2f97.pdf