Molecular and Cellular Dynamics in the Skin, the Lymph Nodes, and the Blood of the Immune Response to Intradermal Injection of Modified Vaccinia Ankara Vaccine

Molecular and Cellular Dynamics in the Skin, the Lymph Nodes, and the Blood of the Immune Response to Intradermal Injection of Modified Vaccinia Ankara Vaccine

New vaccine design approaches would be greatly facilitated by a better understanding of the early systemic changes, and those that occur at the site of injection, responsible for the installation of a durable and oriented protective response. We performed a detailed characterization of very early in...

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Bibliographic Details
Main Authors: Pierre Rosenbaum, Nicolas Tchitchek, Candie Joly, Lev Stimmer, Hakim Hocini, Nathalie Dereuddre-Bosquet, Anne-Sophie Beignon, Catherine Chapon, Yves Levy, Roger Le Grand, Frédéric Martinon
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
vaccine
modified virus Ankara
inflammation
systems biology
non-human primate
skin
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00870/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00870/full

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