Diminished perisomatic GABAergic terminals on cortical neurons adjacent to amyloid plaques

One of the main pathological hallmarks of Alzheimer’s disease (AD) is the accumulation of plaques in the cerebral cortex, which may appear either in the neuropil or in direct association with neuronal somata. Since different axonal systems innervate the dendritic (mostly glutamatergic) and...

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Bibliographic Details
Main Authors: Virginia Garcia-Marin, Lidia Blazquez-Llorca, José-Rodrigo Rodriguez, Susana Boluda, Gerard Muntane, Isidro Ferrer, Javier DeFelipe
Format: Article
Language:English
Published: Frontiers Media S.A. 2009-11-01
Series:Frontiers in Neuroanatomy
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.05.028.2009/full