ATP-Binding Cassette Transporters Modulate Both Coelenterazine- and D-Luciferin-Based Bioluminescence Imaging

Bioluminescence imaging (BLI) of luciferase reporters provides a cost-effective and sensitive means to image biological processes. However, transport of luciferase substrates across the cell membrane does affect BLI readout intensity from intact living cells. To investigate the effect of ATP-binding...

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Bibliographic Details
Main Authors: Ruimin Huang, Jelena Vider, Inna Serganova, Ronald G. Blasberg
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2011-05-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2010.00045