Impact of Hyperhomocysteinemia and Different Dietary Interventions on Cognitive Performance in a Knock-in Mouse Model for Alzheimer’s Disease

Impact of Hyperhomocysteinemia and Different Dietary Interventions on Cognitive Performance in a Knock-in Mouse Model for Alzheimer’s Disease

Background: Hyperhomocysteinemia is considered a possible contributor to the complex pathology of Alzheimer’s disease (AD). For years, researchers in this field have discussed the apparent detrimental effects of the endogenous amino acid homocysteine in the brain. In this study, the roles of hyperho...

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Bibliographic Details
Main Authors: Hendrik Nieraad, Natasja de Bruin, Olga Arne, Martine C. J. Hofmann, Mike Schmidt, Takashi Saito, Takaomi C. Saido, Robert Gurke, Dominik Schmidt, Uwe Till, Michael J. Parnham, Gerd Geisslinger
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Nutrients
Subjects:
hyperhomocysteinemia
vitamin B deficiency
Alzheimer’s disease
amyloid beta-peptides
disease models
animal
Online Access:https://www.mdpi.com/2072-6643/12/11/3248

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https://www.mdpi.com/2072-6643/12/11/3248

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