Age-Dependent Protein Aggregation Initiates Amyloid-β Aggregation

Aging is the most important risk factor for neurodegenerative diseases associated with pathological protein aggregation such as Alzheimer’s disease. Although aging is an important player, it remains unknown which molecular changes are relevant for disease initiation. Recently, it has become apparent...

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Bibliographic Details
Main Authors: Nicole Groh, Anika Bühler, Chaolie Huang, Ka Wan Li, Pim van Nierop, August B. Smit, Marcus Fändrich, Frank Baumann, Della C. David
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00138/full