Limitations of the BCG vaccine and new prophylaxis strategies against human tuberculosis

Limitations of the BCG vaccine and new prophylaxis strategies against human tuberculosis

BCG (Bacille Calmette Guérin), an attenuated vaccine derived from Mycobacterium bovis, is the current vaccine against tuberculosis. Notwithstanding its protection of children, BCG has failed to protect adults against active pulmonary tuberculosis, especially in countries where the disease is endemic...

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Bibliographic Details
Main Authors: Arioldo Carvalho Vasconcelos-Junior, João Alves de Araújo-Filho, Ediane Batista da Silva, Eduardo Martins de Sousa, André Kipnis, Ana Paula Junqueira-Kipnis
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2009-09-01
Series:Einstein (São Paulo)
Subjects:
Tuberculosis/prevention & control
BCG/therapeutic use
Vaccines
DNA/therapeutic use
DNA/administration & dosage
subunit/administration & dosage
Tuberculosis vaccines
Recombinant proteins/immunology
Online Access:http://apps.einstein.br/revista/arquivos/PDF/1333-Einstein%20v7n3p383-9.pdf

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http://apps.einstein.br/revista/arquivos/PDF/1333-Einstein%20v7n3p383-9.pdf

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