Global chromosomal structural instability in a subpopulation of starving Escherichia coli cells.

Copy-number variations (CNVs) constitute very common differences between individual humans and possibly all genomes and may therefore be important fuel for evolution, yet how they form remains elusive. In starving Escherichia coli, gene amplification is induced by stress, controlled by the general s...

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Bibliographic Details
Main Authors: Dongxu Lin, Ian B Gibson, Jessica M Moore, P C Thornton, Suzanne M Leal, P J Hastings
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3161906?pdf=render