Identification of crucial metabolites/reactions in tumor signaling networks
Changes in metabolites/reactions of cell signaling pathways play a key role in tumorigenesis. In present study, betweenness centrality, degree and k-core value of every metabolite/reaction in tumor signaling pathways p53, AKT, Ras, JAK-STAT, TNF, and VEGF were calculated. Crucial metabolites/reactio...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
International Academy of Ecology and Environmental Sciences
2013-12-01
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Series: | Network Biology |
Subjects: | |
Online Access: | http://www.iaees.org/publications/journals/nb/articles/2013-3(4)/crucial-metabolites-reactions-in-tumor-signaling.pdf |