Identification of crucial metabolites/reactions in tumor signaling networks

Changes in metabolites/reactions of cell signaling pathways play a key role in tumorigenesis. In present study, betweenness centrality, degree and k-core value of every metabolite/reaction in tumor signaling pathways p53, AKT, Ras, JAK-STAT, TNF, and VEGF were calculated. Crucial metabolites/reactio...

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Bibliographic Details
Main Authors: JingRon Li, WenJun Zhang
Format: Article
Language:English
Published: International Academy of Ecology and Environmental Sciences 2013-12-01
Series:Network Biology
Subjects:
Online Access:http://www.iaees.org/publications/journals/nb/articles/2013-3(4)/crucial-metabolites-reactions-in-tumor-signaling.pdf