Increased cerebrospinal fluid adenosine 5'-triphosphate in patients with amyotrophic lateral sclerosis

Increased cerebrospinal fluid adenosine 5'-triphosphate in patients with amyotrophic lateral sclerosis

Abstract Background Extracellular adenosine 5'-triphosphate (ATP) has been suggested to cause neuroinflammation and motor neuron degeneration by activating microglia and astrocytes in amyotrophic lateral sclerosis (ALS). Since we have developed a highly sensitive ATP assay system, we examined c...

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Bibliographic Details
Main Authors: Takamasa Nukui, Atsushi Matsui, Hideki Niimi, Tomoyuki Sugimoto, Tomohiro Hayashi, Nobuhiro Dougu, Hirofumi Konishi, Mamoru Yamamoto, Ryoko Anada, Noriyuki Matsuda, Isao Kitajima, Yuji Nakatsuji
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Neurology
Subjects:
ALS
Cerebrospinal fluid
ATP
Biomarker
Online Access:https://doi.org/10.1186/s12883-021-02288-4

Internet

https://doi.org/10.1186/s12883-021-02288-4

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