Silibinin induces apoptosis via calpain-dependent AIF nuclear translocation in U87MG human glioma cell death

<p>Abstract</p> <p>Background</p> <p>Silibinin, a natural polyphenolic flavonoid, has been reported to induce cell death in various cancer cell types. However, the molecular mechanism is not clearly defined. Our previous study showed that silibinin induces glioma cell d...

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Bibliographic Details
Main Authors: Kim Yong K, Kim Jae H, Kwon Chae H, Kim Thae H, Shin Won Y, Jeong Ji C, Kim Ki H
Format: Article
Language:English
Published: BMC 2011-04-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/30/1/44