The Ethanol Extract of Licorice (Glycyrrhiza uralensis) Protects against Triptolide-Induced Oxidative Stress through Activation of Nrf2

To investigate the potential role of nuclear factor erythroid 2-related factor 2 (Nrf2) in licorice ethanol extract (LEE) against triptolide- (TP-) induced hepatotoxicity, HepG2 cells were exposed to LEE (30, 60, and 90 mg·L−1) for 12 h and then treated with TP (50 nM) for 24 h. Besides, an acute li...

Full description

Bibliographic Details
Main Authors: Ling-Juan Cao, Zhen-Yan Hou, Huan-De Li, Bi-Kui Zhang, Ping-Fei Fang, Da-Xiong Xiang, Zhi-Hua Li, Hui Gong, Yang Deng, Yan-Xia Ma, Huai-Bo Tang, Miao Yan
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2017/2752389