Connexin therapeutics: blocking connexin hemichannel pores is distinct from blocking pannexin channels or gap junctions

Compounds that block the function of connexin and pannexin protein channels have been suggested to be valuable therapeutics for a range of diseases. Some of these compounds are now in clinical trials, but for many of them, the literature is inconclusive about the molecular effect on the tissue, desp...

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Bibliographic Details
Main Authors: Monica L Acosta, Mohd N Mat Nor, Cindy X Guo, Odunayo O Mugisho, Frazer P Coutinho, Ilva D Rupenthal, Colin R Green
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=3;spage=482;epage=488;aulast=Acosta