Base-Promoted Chemodivergent Formation of 1,4-Benzoxazepin-5(4<i>H</i>)-ones and 1,3-Benzoxazin-4(4<i>H</i>)-ones Switched by Solvents
The KOH-promoted chemodivergent benzannulation of <i>ortho</i>-fluorobenzamides with 2-propyn-1-ol can afford either 1,4-benzoxazepin-5(4<i>H</i>)-ones or 1,3-benzoxazin-4(4<i>H</i>)-ones in good yields with high selectivity, depending greatly upon the use of solv...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-10-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/24/20/3773 |