Sleep pattern and locomotor activity are impaired by doxorubicin in non-tumor-bearing rats

Purpose: We sought explore the effects of doxorubicin on sleep patterns and locomotor activity. To investigate these effects, two groups were formed: a control group and a Doxorubicin (DOXO) group. Methods: Sixteen rats were randomly assigned to either the control or DOXO groups. The sleep patterns...

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Bibliographic Details
Main Authors: Fabio Santos Lira, Andrea Maculano Esteves, Gustavo Duarte Pimentel, José Cesar Rosa, Miriam Kannebley Frank, Melise Oliveira Mariano, Josiane Budni, João Quevedo, Ronaldo Vagner dos Santos, Marco Túlio de Mello
Format: Article
Language:English
Published: Brazilian Association of Sleep and Latin American Federation of Sleep Societies 2016-07-01
Series:Sleep Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1984006316300827