Liquid Chromatography with Tandem Mass Spectrometry: A Sensitive Method for the Determination of Dehydrodiisoeugenol in Rat Cerebral Nuclei

Liquid Chromatography with Tandem Mass Spectrometry: A Sensitive Method for the Determination of Dehydrodiisoeugenol in Rat Cerebral Nuclei

A new liquid chromatography–tandem mass spectrometry (LC-MS/MS) method is developed for the quantification of dehydrodiisoeugenol (DDIE) in rat cerebral nuclei after single intravenous administration. DDIE and daidzein (internal standard) were separated on a Diamonsil™ ODS C18 column with methanol–w...

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Bibliographic Details
Main Authors: You-Bo Zhang, Xin-Bao Yang, Xiu-Wei Yang, Wei Xu, Fei Li, Frank J. Gonzezal
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Molecules
Subjects:
HPLC-MS/MS
cerebral nuclei
drug distribution
nutmeg
Myristica fragrans
dehydrodiisoeugenol
Online Access:http://www.mdpi.com/1420-3049/21/3/321

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http://www.mdpi.com/1420-3049/21/3/321

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