Liver Cholesterol Overload Aggravates Obstructive Cholestasis by Inducing Oxidative Stress and Premature Death in Mice

Nonalcoholic steatohepatitis is one of the leading causes of liver disease. Dietary factors determine the clinical presentation of steatohepatitis and can influence the progression of related diseases. Cholesterol has emerged as a critical player in the disease and hence consumption of cholesterol-e...

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Bibliographic Details
Main Authors: Natalia Nuño-Lámbarri, Mayra Domínguez-Pérez, Anna Baulies-Domenech, Maria J. Monte, Jose J. G. Marin, Patricia Rosales-Cruz, Verónica Souza, Roxana U. Miranda, Leticia Bucio, Eduardo E. Montalvo-Jave, María Concepción Gutiérrez-Ruiz, Carmen García-Ruiz, José C. Fernández-Checa, Luis Enrique Gomez-Quiroz
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/9895176