Design, Synthesis, Physicochemical and Immunological Characterization of Dendrimer-HBsAg Conjugate

Manufacturing new Hepatitis B virus vaccines, specifically by the use of nanoparticles, is of high global interest. In this paper, a new biocompatible and biodegradable structure of nano-sized hepatitis B virus’ surface antigen (HBsAg) was generated by conjugation with dendrimers, a low cost biodegr...

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Bibliographic Details
Main Authors: Mohammad Sadeq Khosravy, Mehdi Shafiee Ardestani, Reza Ahangari Cohan, Delaram Doroud, Safieh Amini, Seyed Bahman Momen, Seyed Mohammad Atyabi, Hossien Heydari, Rohollah Vahabpour
Format: Article
Language:English
Published: Pasteur Institute of Iran 2014-11-01
Series:Vaccine Research
Subjects:
Online Access:http://vacres.pasteur.ac.ir/article-1-42-en.html