Macrophages improve survival, proliferation and migration of engrafted myogenic precursor cells into MDX skeletal muscle.

Transplantation of muscle precursor cells is of therapeutic interest for focal skeletal muscular diseases. However, major limitations of cell transplantation are the poor survival, expansion and migration of the injected cells. The massive and early death of transplanted myoblasts is not fully under...

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Bibliographic Details
Main Authors: Pierre-François Lesault, Marine Theret, Mélanie Magnan, Sylvain Cuvellier, Yiming Niu, Romain K Gherardi, Jacques P Tremblay, Luc Hittinger, Bénédicte Chazaud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23056408/?tool=EBI