Size-dependent patterns of cell proliferation and migration in freely-expanding epithelia
The coordination of cell proliferation and migration in growing tissues is crucial in development and regeneration but remains poorly understood. Here, we find that, while expanding with an edge speed independent of initial conditions, millimeter-scale epithelial monolayers exhibit internal patterns...
Main Authors: | Matthew A Heinrich, Ricard Alert, Julienne M LaChance, Tom J Zajdel, Andrej Košmrlj, Daniel J Cohen |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-08-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/58945 |
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