Complement Activation in Arterial and Venous Thrombosis is Mediated by Plasmin

Complement Activation in Arterial and Venous Thrombosis is Mediated by Plasmin

Thrombus formation leading to vaso-occlusive events is a major cause of death, and involves complex interactions between coagulation, fibrinolytic and innate immune systems. Leukocyte recruitment is a key step, mediated partly by chemotactic complement activation factors C3a and C5a. However, mechan...

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Bibliographic Details
Main Authors: Jonathan H. Foley, Bethany L. Walton, Maria M. Aleman, Alice M. O'Byrne, Victor Lei, Micaela Harrasser, Kimberley A. Foley, Alisa S. Wolberg, Edward M. Conway
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:EBioMedicine
Subjects:
Thrombosis
Complement
Leukocytes
Thrombin
Fibrinolysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416300445

Internet

http://www.sciencedirect.com/science/article/pii/S2352396416300445

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