The association of diabetes mellitus and insulin treatment with expression of insulin-related proteins in breast tumors

The association of diabetes mellitus and insulin treatment with expression of insulin-related proteins in breast tumors

Abstract Background The insulin receptor (INSR) and the insulin growth factor 1 receptor (IGF1R) play important roles in the etiology of both diabetes mellitus and breast cancer. We aimed to evaluate the expression of hormone and insulin-related proteins within or related to the PI3K and MAPK pathwa...

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Bibliographic Details
Main Authors: Heleen K. Bronsveld, Marie L. De Bruin, Jelle Wesseling, Joyce Sanders, Ingrid Hofland, Vibeke Jensen, Marloes T. Bazelier, Bas ter Braak, Anthonius de Boer, Peter Vestergaard, Marjanka K. Schmidt
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Cancer
Subjects:
Insulin
Insulin growth factor 1 receptor
Diabetes mellitus
Breast cancer
PI3K pathway
MAPK pathway
Online Access:http://link.springer.com/article/10.1186/s12885-018-4072-8

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http://link.springer.com/article/10.1186/s12885-018-4072-8

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