Isoquinolinequinone Derivatives from a Marine Sponge (<i>Haliclona</i> sp.) Regulate Inflammation in In Vitro System of Intestine

Isoquinolinequinone Derivatives from a Marine Sponge (<i>Haliclona</i> sp.) Regulate Inflammation in In Vitro System of Intestine

Using bio-guided fractionation and based on the inhibitory activities of nitric oxide (NO) and prostaglandin E2 (PGE2), eight isoquinolinequinone derivatives (<b>1</b>–<b>8</b>) were isolated from the marine sponge <i>Haliclona</i> sp. Among these, methyl <i>...

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Bibliographic Details
Main Authors: Yun Na Kim, Yeong Kwang Ji, Na-Hyun Kim, Nguyen Van Tu, Jung-Rae Rho, Eun Ju Jeong
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Marine Drugs
Subjects:
isoquinolinequinone
<i>Haliclona</i> sp.
inflammation
intestine
inflammatory bowel disease
co-culture
Online Access:https://www.mdpi.com/1660-3397/19/2/90

Internet

https://www.mdpi.com/1660-3397/19/2/90

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