How p53 Molecules Solve the Target DNA Search Problem: A Review

Interactions between DNA and DNA-binding proteins play an important role in many essential cellular processes. A key function of the DNA-binding protein p53 is to search for and bind to target sites incorporated in genomic DNA, which triggers transcriptional regulation. How do p53 molecules achieve...

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Bibliographic Details
Main Authors: Kiyoto Kamagata, Yuji Itoh, Dwiky Rendra Graha Subekti
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
p53
dna
Online Access:https://www.mdpi.com/1422-0067/21/3/1031