Tumor-Penetrating Delivery of siRNA against TNFα to Human Vestibular Schwannomas

Abstract Vestibular schwannoma (VS) is the most common tumor of the cerebellopontine angle, and it typically presents with sensorineural hearing loss. The genomic landscape of schwannoma is complex and many of the molecules implicated in VS pathogenesis represent targets not amenable to antibody-bas...

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Bibliographic Details
Main Authors: Yin Ren, Jessica E. Sagers, Lukas D. Landegger, Sangeeta N. Bhatia, Konstantina M. Stankovic
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-13032-9