Structural and Functional Changes in the Na<sup>+</sup>/H<sup>+</sup> Exchanger Isoform 1, Induced by Erk1/2 Phosphorylation
The human Na<sup>+</sup>/H<sup>+</sup> exchanger isoform 1 (NHE1) is a plasma membrane transport protein that plays an important role in pH regulation in mammalian cells. Because of the generation of protons by intermediary metabolism as well as the negative membrane potentia...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-05-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/20/10/2378 |